Reconstructed human epidermis, full-thickness skin, vaginal epithelium, and disease-specific models — built from primary cells, validated against native histology.
Our BioDEpi family is constructed using normal epidermal keratinocytes sourced from human tissues after obtaining ethical consent. Isolated and cultured in in-house developed serum-free media, these cells form multilayered, highly differentiated models that faithfully mimic the native human epidermis — including stratum basale (expressing p63 and Ki-67), stratum spinosum, stratum granulosum (involucrin, keratin 10), and a fully functional stratum corneum.
“The resemblance of the BioDEpi model to the native human epidermis highlights its authenticity and suitability for various applications — from dermatological studies to drug development.”
From everyday irritation testing to disease-specific drug screening. Click any model for status, formats and applications.
BioDAcne
BioDEpi infected with C. acnes — confirmed acneiform structures, TEER decline, disrupted stratum corneum and elevated TNF-α / acne gene expression.
BioDFT
Combined dermal + epidermal construct: a collagen matrix populated with viable fibroblasts beneath a stratified, keratinized epidermis. Highly predictive of barrier properties and sub-surface interactions.
BioDEpi
3D reconstructed epidermis from primary human keratinocytes. Recapitulates stratum corneum, basale, spinosum and granulosum. Verified free of HIV, hepatitis, mycoplasma and microbial contamination.
BioDVag
Multilayered, stratified squamous epithelium mimicking the human vaginal mucosal barrier, for femcare safety and efficacy work.
BioDPsor
Reconstructed psoriatic skin for treatments targeting keratinocyte hyperproliferation and inflammatory markers.
BioDPigma
Keratinocytes + melanocytes localised in the basal layer, across three phototypes (II, IV, VI) for diverse skin tones.
In the R&D pipeline
Tissue families we're actively developing — ask if a model on this list could anchor your study.
When a clinical study is overkill or off-limits, our reconstructed-tissue platforms deliver human-relevant evidence at a fraction of the cost and risk.
We build bespoke tissue platforms — from custom co-cultures to fully novel disease models. Tell us what you'd like to assay.
